RBL-C5aR cell line

Scientists at the University of Göttingen developed a transfectant RBL-C5aR cell line which is able to express more than 1 million C5a receptors on its cell surface, showing a specific high Ca2+ signal. The generated RBL-cells express C5aR in a number of „flavours“ (FLAG-tagged, N-glycosilation deficient, phosphorylation-deficient, co-transfected with other GPCR). C5aR(CD88) binds to C5a, an important chemotactic protein, element of the biochemical cascade of the complement system. This cell line would make the development of a standardized assay easy, fast, reproducible and sensitive.

Further Information: PDF

MBM ScienceBridge GmbH
Phone: (0551) 30724-152

Contact
Dr. Jens-Peter Horst

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Finding the ship that sent out a warning to The Titanic

New powerful technology reveals lost seabed structures. The ship which sent an iceberg warning to the RMS Titanic, before the ocean-liner sank, has been identified lying in the Irish Sea….

Quantum technology reaches unprecedented control over captured light

Researchers in quantum technology at Chalmers University of Technology have succeeded in developing a technique to control quantum states of light in a three-dimensional cavity. In addition to creating previously…

A master regulator controlling fungal infection of wheat

The fungus Zymoseptoria tritici causes Septoria tritici blotch, the most destructive fungal disease of wheat grown in temperate climates worldwide. This disease reduces wheat yields by 5-10% per year, causing…

Partners & Sponsors