well-fed – Microtiterplate as fed batch reactor system

The Chair of Biochemical Engineering at RWTH Aachen

University developed a novel fermentation method for fedbatch operating conditions, based on Microtiterplates (MTPs). The invention well-fed employs a modified MTP as bioreactor. A 96 well-fed MTP consists of two sets of wells with corresponding channels. One set of wells is acting as feed reservoir, containing feed solution, while the other set of wells is used as culture vessel for microorganisms. These wells are connected through microchannels for controlling the feeding process. The standard well dimension allows the online monitoring and microscopic screening of the culture wells.

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