Synthetic K receptor agonist for pain therapy – Novel class of k selective opioids for peripheral pain treatment

Natural and synthetic opioids are effective and widely

used drugs for the treatment of acute, post-operative or malignant pain. These drugs interact predominantly with μ-opioid receptors in the central nervous system. While being strong analgesics, these drugs also cause severe side effects due to their interaction with μ-opioid receptors in the brain. This limits the use of currently available opioids for palliative care. Not many drugs are available for the treatment of severe peripheral, chronic, neuropathic or non-malignant pain. However, k-opioid receptor agonists with high k receptor affinity and selectivity, which cannot pass the blood brain barrier, are suitable for this purpose. At the University of Münster, a new class of compounds with high k receptor affinity and selectivity as well as strong analgesic effects has been developed.

Further Information: PDF

PROvendis GmbH
Phone: +49 (0)208/94105 0

Contact
Dipl.-Ing. Alfred Schillert

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Enhancing the workhorse

Artificial intelligence, hardware innovations boost confocal microscope’s performance. Since artificial intelligence pioneer Marvin Minsky patented the principle of confocal microscopy in 1957, it has become the workhorse standard in life…

In the quantum realm, not even time flows as you might expect

New study shows the boundary between time moving forward and backward may blur in quantum mechanics. A team of physicists at the Universities of Bristol, Vienna, the Balearic Islands and…

Hubble Spots a Swift Stellar Jet in Running Man Nebula

A jet from a newly formed star flares into the shining depths of reflection nebula NGC 1977 in this Hubble image. The jet (the orange object at the bottom center…

Partners & Sponsors