Marker-free chromosome screening

Researchers at Reutlingen University have succeeded in developing a label-free method for the characterization of metaphase chromosomes. The method and the corresponding analysis algorithm allow for visualization of both the chemical properties (absorption) and the morphological properties (stray light) of a chromosome. Using this method, the bands and sub-bands can be characterized with high resolution. Thus, no staining is required for unambiguous identification. The technology can be integrated into all imaging methods (e.g.microscopy).

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