GEF-Inhibitors: New small molecules for the treatment of autoimmune and malignant diseases

Scientists at the University of Bonn have identified new small molecules which can be used for the treatment of diseases characterized by alterations of proteins which are affected by Guanine nucleotide Exchange Factors (GEFs). Proteins targeted by GEFs are involved in integrin signalling, vesicle transport, or MAPK-signalling. These processes play an important role in the modulation of the immune response. Therefore, abnormal activation of the target proteins of GEFs can cause autoimmune and tumor diseases in humans.

Further Information: PDF

PROvendis GmbH
Phone: +49 (0)208/94105 10

Contact
Dipl.-Ing. Alfred Schillert

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Finding the ship that sent out a warning to The Titanic

New powerful technology reveals lost seabed structures. The ship which sent an iceberg warning to the RMS Titanic, before the ocean-liner sank, has been identified lying in the Irish Sea….

Quantum technology reaches unprecedented control over captured light

Researchers in quantum technology at Chalmers University of Technology have succeeded in developing a technique to control quantum states of light in a three-dimensional cavity. In addition to creating previously…

A master regulator controlling fungal infection of wheat

The fungus Zymoseptoria tritici causes Septoria tritici blotch, the most destructive fungal disease of wheat grown in temperate climates worldwide. This disease reduces wheat yields by 5-10% per year, causing…

Partners & Sponsors