mammalian target of rapamycin

New leukemia treatment offers hope

An antibody drug that targets a surface marker on cancer stem cells could offer a promising new therapeutic approach for treating acute myeloid leukemia (AML),…

New Insights into the Signaling Network of the Vital Protein mTOR

The research group of Prof. Michael N. Hall at the Biozentrum of the University of Basel has now identified a number of new mTOR-regulated proteins, including…

Cancer therapy: A role for MAPK inhibitors combined with mTORC1 inhibitors

Since then, several rapamycin analogs known as mTOR (mammalian target of rapamycin) inhibitors have been tested in clinical trials for the treatment of various…