Determining effective magnetic moment of multicore nanoparticles
Magnetic nanoparticles, a class of nanoparticles that can be manipulated by magnetic fields, have a wide range of technical and biomedical applications, including magnetic hyperthermia, targeted drug delivery, new magnetic storage media and nanorobots.
Most commercial nanoparticles do not possess a single magnetic core but have a number of small magnetic crystals called crystallites.
The important question for researchers is how these crystallites behave inside a multicore nanoparticle and how they respond to an applied magnetic field. A paper in the Journal of Applied Physics, from AIP Publishing, compares the effective magnetic moments of different multicore nanoparticle systems and shows that they are magnetic-field dependent.
“The effective magnetic moment of such a multicore nanoparticle depends on various parameters, such as the size of magnetic crystallites, their packing density, core configuration and the magnetic interaction between them,” said Frank Ludwig, one of the authors of the paper.
Many experimental findings indicate that the ensemble of crystallites behaves like a single magnetic core with some effective magnetic moment. Research has been directed toward determining how this effective magnetic moment is related to the number and size of crystallites inside one multicore nanoparticle because many applications require a large magnetic moment, which, e.g., determines the strength of the magnetic force needed for their manipulation.
The paper's findings are important for researchers optimizing magnetic nanoparticles for various applications, including magnetic hyperthermia and magnetic drug targeting, two new frontiers in cancer therapy.
In magnetic hyperthermia, the nanoparticles are located at the tumor cells. A magnetic field with a frequency and amplitude that will heat the nanoparticles to a temperature of approximately 42-44 degrees Celsius is applied, which kills the tumor cells.
In magnetic drug targeting, the capsule with drugs and magnetic particles is directed to the tumor by magnetic field gradients. When they arrive at the tumor, the drugs are released from the capsule by various techniques. Targeted drug therapy can result in dramatic reduction of doses and side effects versus traditional chemotherapy.
Technical applications of nanoparticles range from new magnetic storage media to nanorobots. Storage media made of nanoparticles are much smaller than existing media and can store greater amounts of data. Nanorobots are machines that can build and manipulate things precisely at an atomic level and can be used in a wide variety of contexts such as miniscule sensors that monitor blood chemistry.
Ludwig said continuing to gain a better understanding of the effective magnetic moment of multicore nanoparticles and, especially, its field dependence is essential for both basic science and applications.
The article, “Magnetic field dependence of the effective magnetic moment of multi-core nanoparticles,” is authored by Tamara Kahmann and Frank Ludwig. The article will appear in the Journal of Applied Physics on June 16, 2020 (DOI: 10.1063/5.0011629). After that date, it can be accessed at https:/
ABOUT THE JOURNAL
The Journal of Applied Physics is an influential international journal publishing significant new experimental and theoretical results in all areas of applied physics. See https:/
Alle Nachrichten aus der Kategorie: Physics and Astronomy
This area deals with the fundamental laws and building blocks of nature and how they interact, the properties and the behavior of matter, and research into space and time and their structures.
innovations-report provides in-depth reports and articles on subjects such as astrophysics, laser technologies, nuclear, quantum, particle and solid-state physics, nanotechnologies, planetary research and findings (Mars, Venus) and developments related to the Hubble Telescope.
Argonne targets lithium-rich materials as key to more sustainable cost-effective batteries
Next-generation batteries using lithium-rich materials could be more sustainable and cost-effective, according to a team of researchers with the U.S. Department of Energy’s (DOE) Argonne National Laboratory. The pivotal discovery,…
Why disordered light-harvesting systems produce ordered outcomes
Scientists typically prefer to work with ordered systems. However, a diverse team of physicists and biophysicists from the University of Groningen found that individual light-harvesting nanotubes with disordered molecular structures…
RadarGlass – from vehicle headlight to radar transceiver
As a result of modern Advanced Driver Assistance Systems, the use of radar technology has become indispensable for the automotive sector. With the installation of a large and growing number…