Mathematicians help unlock secrets of the immune system
The mathematicians, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), will investigate how the different cellular components of the immune system work together and devise a theoretical and computational model that can be used by immunologists, mathematicians, computer scientists, physicists and engineers.
The model promises to help a multi-disciplinary research community work together to bring about medical advances for patients. The project, the Immunology Imaging and Modelling (I2M) Network, is highlighted in the quarterly research highlights magazine of the Biotechnology and Biological Sciences Research Council (BBSRC) this week.
The immune system is one of the most fascinating and complex systems in the human body and scientists still do not fully understand how it works. Immunology has traditionally been a qualitative science, describing the cellular and molecular components of the immune system and their functions. However, to advance our understanding of how the body fights disease there is a pressing need to better understand how the components work together as a whole and provide this information in a quantitative format which can be accessed by the entire scientific community.
Dr Carmen Molína-Paris, network co-ordinator and researcher at the University of Leeds, explains: “A multi and cross-disciplinary, cohesive and active approach is urgently required. The ability to track parasites and cells in real time using novel imaging techniques is allowing exciting new insights and will help us measure the interactions between the different parts of the immune system. This will provide a theoretical and computational model of the immune system, giving a complete picture that researchers from across all disciplines can refer to and draw upon.
“Mathematical immunology is maturing into a discipline where modelling helps everyone to interpret data and resolve controversies. Most importantly, it suggests novel experiments allowing for better and more quantitative interpretations.”
Steve Visscher, interim Chief Executive of BBSRC commented: “The new insight that this model will provide will naturally benefit the patient with the advances in healthcare it will lead to. BBSRC is committed to developing an active and cohesive cross-disciplinary community at the mathematics biology interface to enable a more quantitative and predictive biology.”
All latest news from the category: Life Sciences and Chemistry
Articles and reports from the Life Sciences and chemistry area deal with applied and basic research into modern biology, chemistry and human medicine.
Valuable information can be found on a range of life sciences fields including bacteriology, biochemistry, bionics, bioinformatics, biophysics, biotechnology, genetics, geobotany, human biology, marine biology, microbiology, molecular biology, cellular biology, zoology, bioinorganic chemistry, microchemistry and environmental chemistry.
Creating a reference map to explore the electronic device mimicking brain activity
Maps are essential for exploring trackless wilderness or vast expanses of ocean. The same is true for scientific studies that try to open up new fields and develop brand-new devices….
Arase satellite uncovers coupling between plasma waves and charged particles in Geospace
Scientists unravel a bit more of the mystery underlying how wave-particle interactions generate other plasma waves in Geospace. In a new study published in Physical Review Letters, researchers from Japan…