Researchers identify decision-making area of the brain

New research from investigators in the Centre for Neuroscience Studies at Queen’s University and the Centre for Brain and Mind at The University of Western Ontario has provided the first neuro-imaging evidence that the brain’s frontal lobes play a critical role in planning and choosing actions.

Their study is published today in the journal Nature Neuroscience.

The research team has found that a small region in the frontal lobe of the human brain is selectively activated when an individual intends to make a particular action and not another. These findings help explain why individuals with frontal lobe damage sometimes act impulsively and often have problems making decisions.

“We have identified signals in the normal human brain that we can now investigate in patients with neurological or psychiatric disorders that affect frontal lobe function,” says team member Doug Munoz, professor in the Departments of Physiology and Psychology at Queen’s, and holder of a Canada Research Chair in Neuroscience. “For example, subjects diagnosed with attention-deficit hyperactivity disorder should produce different patterns of brain activation that we can identify. We will then be able to see if these patterns change when they are treated with medication.”

The lead author on the paper is Jason Connolly, a neuroscience graduate student at Western. Other members of the team include Dr. Munoz from Queen’s, and Mel Goodale and Ravi Menon from Western.

The researchers used a new fMRI “single-event” method to study the changes in blood flow in the frontal lobes as volunteers prepared to perform one of two different kinds of movements when a visual target was presented. Not only did the signals in the frontal lobes build up over time as the volunteers got ready to respond, but the nature of the activity varied and depended on whether they were planning to make one kind of movement rather than another.

Future experiments by the research team will explore how these frontal circuits interact with other areas of the brain in the planning and control of everyday behaviour, as well as investigating patient groups.

Contacts:

Nancy Dorrance, Queen’s News & Media Services, 613.533.2869
David Pulver, Queen’s News & Media Services, 613.533.6000 ext. 77559

Media Contact

Nancy Dorrance EurekAlert!

All latest news from the category: Life Sciences and Chemistry

Articles and reports from the Life Sciences and chemistry area deal with applied and basic research into modern biology, chemistry and human medicine.

Valuable information can be found on a range of life sciences fields including bacteriology, biochemistry, bionics, bioinformatics, biophysics, biotechnology, genetics, geobotany, human biology, marine biology, microbiology, molecular biology, cellular biology, zoology, bioinorganic chemistry, microchemistry and environmental chemistry.

Back to home

Comments (0)

Write a comment

Newest articles

World’s smallest molecular machine

… reversible sliding motion in ammonium-linked ferrocene. Researchers stabilized ferrocene molecules on a flat substrate for the first time, creating an electronically controllable sliding molecular machine. Artificial molecular machines, nanoscale…

Towards the control of chemical reactions

Overcoming one of the challenges of quantum mechanics: A major result in quantum mechanics has been achieved: for the first time, the temporal evolution of a quantum system has been…

Planets form through domino effect

New radio astronomy observations of a planetary system in the process of forming show that once the first planets form close to the central star, these planets can help shepherd…