Peptides for Diagnosis and Therapy of Celery Allergy and of Hazelnut Allergy

<strong>Background</strong><br>

Celery is a frequent cause of food allergy in pollen-sensitized patients and may induce severe allergic reactions. Allergic reactions against celery are of major clinical relevance due to celery's wide presence in convenience foods and spice. Approximately 3% – 4% of the European and American population and 5% of young children are affected by immunoglobulin E (IgE) mediated food allergy. The symptoms ranging from mild oral pruritus to a possible life-threatening anaphylactic shock.</p> <strong>Technology</strong><br> We offer novel linear IgE-binding peptide epitopes of the major celery aller-gen Api g1 for the diagnosis and therapy of celery allergy. The peptides can also serve as a basis for the detection of traces of Api g1 allergens in food and other products. Based on the novel peptides, a high specific assay was developed which allows the differentiation between celery allergic patients and healthy individuals.</p> <b>Benefits:</b> <ul> <li>Highly specific diagnosis of celery allergic patients (IgE detection)</li> <li>Assay allows a reliable, rapid and easy diagnosis</li> <li>Peptides are usable for chip and other high throughput applications</li> <li>Peptides might be suitable for a specific desensitization of patients (Immunotherapy)</li> <li>Antibodies against these peptides can be used for the detection of traces of celery in food and other products</li> </ul><br> <p><strong>IP Rights</strong><br> EP application (July 2010)<br> PCT application (July 2011) <br> <br> <strong>Origin</strong><br> The invention was made at the Charité – Universitätsmedizin Berlin.</p> <b>Find the technology offer and contact details here: <a href=”http://www.ipal.de/technologieangebote/10048″ target=”_blank”>http://www.ipal.de/technologieangebote/10048</a></b>

Further Information: PDF

ipal GmbH
Phone: +49 (0)30/2125-4820

Contact
Dr. Dirk Dantz

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Lighting up the future

New multidisciplinary research from the University of St Andrews could lead to more efficient televisions, computer screens and lighting. Researchers at the Organic Semiconductor Centre in the School of Physics and…

Researchers crack sugarcane’s complex genetic code

Sweet success: Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants….

Evolution of the most powerful ocean current on Earth

The Antarctic Circumpolar Current plays an important part in global overturning circulation, the exchange of heat and CO2 between the ocean and atmosphere, and the stability of Antarctica’s ice sheets….

Partners & Sponsors