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Parenteral controlled drug delivery - oleogels

10.02.2017

Parenteral controlled drug delivery is of crucial importance for the pharmacotherapy of many diseases (e.g. breast and prostate cancer, local inflammation). By means of controlled release systems it is possible to decrease the frequency of administration (from hours to months), to increase drug efficiency and to decrease side effects. Direct Injectable OleoGels (DIOGs) and In Situ Forming OleoGels (ISFOGs) were developed as new, biodegradable and lipid based formulations for parenteral controlled release applications. Both formulations have many advantages in terms of manufacturability, rheological properties and release control compared to the currently used drug delivery systems.

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