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Novel Modulators of TRAIL Signalling Pathway

30.12.2014

The TNF-Related Apoptosis-Inducing Ligand (TRAIL) has been shown to be involved in apoptosis, cell survival, migration and proliferation. DKFZ inventors identified a multitude of genes encoding proteins that are associated with cell death induction by TRAIL. According to its individual function, inhibition or activation of the respective gene or gene product is assumed to have beneficial effects on cancer treatment. The technology can be used to screen for small molecules, antibodies or siRNAs that are capable of modulating TRAIL-induced cell death, thus having the potential to kill cancer cells or to sensitize cancer cells to established cancer drugs.

Further information: PDF

DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
Phone: +49-6221-42 2955

Contact
Dr. Ruth Herzog

As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=03902&lang=en
http://www.technologieallianz.de/

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