Biocatalytic Friedel-Crafts Acylations
This technology provides a biocatalytic method for the regioselective monoacylation of
phenols or aminophenols serving as acyl acceptors in the presence of acyl donor molecules
of the formula R2-C(=O)-R3 and acyl transferase (ATase) enzymes as catalysts. The produced
phenols can be used in different markets, such as cosmetics, aroma (natural), industrial
enzymes (5 billion US$ p.a.), biocatalysis, pharmaceutical industry, agricultural chemistry,
biological pesticides.
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