Bioactive pre-tubulysins and use thereof
Pre-tubulysin was already claimed as a hypothetically common preliminary stage of tubulysins in 2004. Now it is available by synthesis and can be used for increasing the output of tubulysin production by implementing it in tubulysin producing hosts. Besides the possibility to obtain tubulysin by biotransformation of pre-tubulysin, the later shows high biological activity by itself and therefore might be useful in cancer therapy as an self-contained agent.
Further Information: PDF
Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-6340
Contact
Dr. Dipl. Chem. Anne Seifert, Dipl.-Kfm. Axel Koch MBA, Dipl.-Ing. Gerd Schneider
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Making diamonds at ambient pressure
Scientists develop novel liquid metal alloy system to synthesize diamond under moderate conditions. Did you know that 99% of synthetic diamonds are currently produced using high-pressure and high-temperature (HPHT) methods?[2]…
Eruption of mega-magnetic star lights up nearby galaxy
Thanks to ESA satellites, an international team including UNIGE researchers has detected a giant eruption coming from a magnetar, an extremely magnetic neutron star. While ESA’s satellite INTEGRAL was observing…
Solving the riddle of the sphingolipids in coronary artery disease
Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new…