Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pain may interfere with depression improvement

29.01.2004


Treatment for depression may be stymied in people with moderate to severe body pain, according to a new study.

Researchers Matthew J. Bair, M.D., formerly of the Regenstrief Institute, and colleagues uncovered the connection by analyzing the results of a clinical trial of 573 depression patients taking medications like Prozac, Paxil or Zoloft. Their findings are published in the journal Psychosomatic Medicine.

Although depression improved in most of the patients after three months of drug therapy, 24 percent had persistently high depression scores. The therapy was most likely to fail among those who reported moderate to severe pain at the beginning of their treatment.



“In particular, the odds of a poor depression treatment response were twice as high in patients with moderate pain at baseline and three to four times as high in those with severe pain,” Bair says.

Factors like pain may help explain why antidepressants have a mixed record of success, Bair says. Between 50 and 70 percent of depressed patients find only partial relief with their medications.

Researchers have long known that pain and depression often go hand in hand, but there are few studies of how pain might affect depression treatment. In the Bair study, more than two-thirds of the patients reported some degree of pain at the start of their treatment. Twenty-five percent said their pain was mild, 30 percent had moderate pain and 14 percent said they had severe pain.

“We believe a treatment model that incorporates assessment and treatment of both depression and pain is desirable,” Bair says.

The study was supported by the Health Resources and Service Administration and Eli Lilly and Co.



Health Behavior News Service: (202) 387-2829 or www.hbns.org.
Interviews: Contact Matthew Bair at mbair@iupui.edu.
Psychosomatic Medicine: Contact Victoria White at (352) 376-1611, ext. 5300, or psychosomatic@medicine.ufl.edu. Online, visit www.psychosomaticmedicine.org.

Becky Ham | Health Behavior News Service
Further information:
http://www.hbns.org/news/pain01-28-04.cfm

More articles from Social Sciences:

nachricht New measure for the wellbeing of populations could replace Human Development Index
07.11.2018 | International Institute for Applied Systems Analysis (IIASA)

nachricht Because not only arguments count
30.10.2018 | Max-Planck-Institut für Mathematik in den Naturwissenschaften (MPIMIS)

All articles from Social Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The hidden structure of the periodic system

The well-known representation of chemical elements is just one example of how objects can be arranged and classified

The periodic table of elements that most chemistry books depict is only one special case. This tabular overview of the chemical elements, which goes back to...

Im Focus: MPSD team discovers light-induced ferroelectricity in strontium titanate

Light can be used not only to measure materials’ properties, but also to change them. Especially interesting are those cases in which the function of a material can be modified, such as its ability to conduct electricity or to store information in its magnetic state. A team led by Andrea Cavalleri from the Max Planck Institute for the Structure and Dynamics of Matter in Hamburg used terahertz frequency light pulses to transform a non-ferroelectric material into a ferroelectric one.

Ferroelectricity is a state in which the constituent lattice “looks” in one specific direction, forming a macroscopic electrical polarisation. The ability to...

Im Focus: Determining the Earth’s gravity field more accurately than ever before

Researchers at TU Graz calculate the most accurate gravity field determination of the Earth using 1.16 billion satellite measurements. This yields valuable knowledge for climate research.

The Earth’s gravity fluctuates from place to place. Geodesists use this phenomenon to observe geodynamic and climatological processes. Using...

Im Focus: Tube anemone has the largest animal mitochondrial genome ever sequenced

Discovery by Brazilian and US researchers could change the classification of two species, which appear more akin to jellyfish than was thought.

The tube anemone Isarachnanthus nocturnus is only 15 cm long but has the largest mitochondrial genome of any animal sequenced to date, with 80,923 base pairs....

Im Focus: Tiny light box opens new doors into the nanoworld

Researchers at Chalmers University of Technology, Sweden, have discovered a completely new way of capturing, amplifying and linking light to matter at the nanolevel. Using a tiny box, built from stacked atomically thin material, they have succeeded in creating a type of feedback loop in which light and matter become one. The discovery, which was recently published in Nature Nanotechnology, opens up new possibilities in the world of nanophotonics.

Photonics is concerned with various means of using light. Fibre-optic communication is an example of photonics, as is the technology behind photodetectors and...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

SEMANTiCS 2019 brings together industry leaders and data scientists in Karlsruhe

29.04.2019 | Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

 
Latest News

Novel communications architecture for future ultra-high speed wireless networks

17.06.2019 | Information Technology

Climate Change in West Africa

17.06.2019 | Earth Sciences

Robotic fish to replace animal testing

17.06.2019 | Ecology, The Environment and Conservation

VideoLinks
Science & Research
Overview of more VideoLinks >>>