Stomach MRI images combined with functional fMRI of the brain activity have provided scientists new insight into how the brain listens to the stomach during eating
Stomach MRI images combined with functional fMRI of the brain activity have provided scientists new insight into how the brain listens to the stomach during eating. Research from Wageningen University in the Netherlands shows - for the first time - real time data of the brain, the stomach, and people's feelings of satiety measured simultaneously during a meal, in a study to be reported this week at the annual meeting of the Society for the Study of Ingestive Behavior, held in Porto, Portugal. The researchers collected data from 19 participants during two separate sessions with different consumption procedures and found that a simple change like drinking more water can alter messages from the stomach interpreted as fullness by the brain. This new research approach can be used to investigate the interplay between satiety feelings, volume of the stomach and activity in the brain.
In the experiment, participants drank a milk-shake on an empty stomach, which was followed by a small (50 mL) or large glass of water (350 mL). MRI images were used to see how the different amounts of water affected stretching of the stomach: the large glass of water doubled the stomach content compared to the small glass. Together with this larger volume subjects reported to have less hunger and felt fuller.
This novel approach - combining information obtained simultaneously from MRI images of the stomach, feelings reported by the subjects, and brain scans - can offer new insights which would otherwise have been unknown, for example that activation in a brain area called the mid-temporal gyrus seems is in some way influenced by the increased water load in this experiment. The Wageningen University scientists developed the combined MRI method as part of the European Nudge-it research project, which seeks to discover simple changes that promote healthier eating. They will use it to search for a brain signature that leads people to decide to stop eating, to determine how strategies like water with a meal can be effective at feeling fuller sooner.
"Combining these types of measurements is difficult, because MRI scanners are usually set-up to perform only one type of scan. We've been able to very quickly switch the scanner from one functionality to another to do this type of research" says Guido Camps, lead author of the study. "In conclusion, we've found that simply adding water increases stomach distension, curbs appetite in the short term and increases regional brain activity."
Activation in the insula is increased when the stomach is distended more.
The same subject with either the small (left) or large volume of water (right) in the stomach (delineated in red).
Research: "Just add water: how water affects gastric distension, appetite and brain activity"
G CAMPS, R VEIT, M MARS, C DE GRAAF, P SMEETS
Melissa Szkodzinska | EurekAlert!
New measure for the wellbeing of populations could replace Human Development Index
07.11.2018 | International Institute for Applied Systems Analysis (IIASA)
Because not only arguments count
30.10.2018 | Max-Planck-Institut für Mathematik in den Naturwissenschaften (MPIMIS)
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
14.12.2018 | Power and Electrical Engineering
14.12.2018 | Physics and Astronomy
14.12.2018 | Physics and Astronomy