An estimated 17% of human cancers are caused by chronic infection. Cancer results from the progressive accumulation of genetic changes to the body’s healthy regulation of cell growth. It arises when these changes cause cells to proliferate uncontrollably. The International Agency for Research on Cancer recognizes 9 viral and bacterial agents that appear to provoke this biological chain of events.
“INCA will help researchers develop new prevention measures and treatments against cancers such as leukemia, stomach cancer, and cervical cancer”, explained Professor Thomas Schulz, INCA’s principal coordinator based at Hannover Medical School, Germany. The consortium will focus on five viruses and one bacterium, the gut-dwelling Helicobacter pylori, to investigate how chronic infections and inflammation can interfere with normal cellular functioning.
Techniques like gene expression profiling reveal 100’s or even thousands of genes that are apparently active in a particular disease state. Such results require specialized statistical processing. INCA will exploit existing biological knowledge of inflammatory pathways to interpret high throughput data measuring transcriptomic, proteomic and metabolomic activity. Professor Schulz added, “Genedata’s informatics resources will help us gain the best advantage from genome-wide experimental investigations”.
“We are proud to provide the research informatics infrastructure for this important cancer research program”, says Dr. Othmar Pfannes, CEO of Genedata AG. Genedata will integrate high throughput molecular data and provide quantitative data analysis and training services. Dr. Pfannes added, “Our computational solutions are tailored for collaborative settings and provide a valuable informatics foundation for consortia-based research efforts”.
Tobe Freeman | alfa
Cebit 2018: Saarbrücken Start-up combines Tinkering and Programming for Elementary School Kids
05.06.2018 | Universität des Saarlandes
The classroom of tomorrow – DFKI and TUK open lab for new digital teaching and learning methods
03.05.2018 | Deutsches Forschungszentrum für Künstliche Intelligenz GmbH, DFKI
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences