Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Tiny cell-based chemical detectors have homeland security potential

14.03.2003


A highly sensitive, inexpensive "lab-on-a-chip" that provides warning within seconds of even trace amounts of toxic chemicals in water was designed and demonstrated recently by National Institute of Standards and Technology (NIST) scientists and collaborators.



The prototype sensor system monitors the natural response of bacterial cells bound within the microscopic channels of a plastic microfluidics device--a miniaturized chemical and biochemical analysis system. In the presence of certain chemicals, the cells eject large amounts of potassium, which is detected with an optical sensor that changes color. The prototype was demonstrated as part of an early warning system for industrial pollutants that interfere with sewage treatment, but it also has potential homeland security applications.

Cell-based sensors are of great interest today because they can respond to a wide range of chemical toxins rapidly. NIST’s primary contributions to this project involve expertise in microfluidics technology, particularly aspects such as plastics processing. The new device has a novel configuration in which, through the use of lasers, tiny posts are constructed within the channels to act as a sieve and promote adhesion of the cells.


Although this type of chemical test could be performed in other formats, a microfluidics device is more sensitive because of the high surface to volume ratio, and also faster because of the close juxtaposition of chemicals and cells. In addition, it consumes less reagent and sample material and could be used in a distributed sensor network for real-time field testing. The device was designed in collaboration with scientists at Virginia Polytechnic Institute and State University (Blacksburg, Va.) and Veridian Pacific-Sierra Research (Charlottesville, Va.).


For more information, contact Laurie Locascio, 301-975-3130, laurie.locascio@nist.gov.

Laura Ost | EurekAlert!
Further information:
http://www.nist.gov/

More articles from Process Engineering:

nachricht New technology for ultra-smooth polymer films
28.06.2018 | Fraunhofer-Institut für Organische Elektronik, Elektronenstrahl- und Plasmatechnik FEP

nachricht Diamond watch components
18.06.2018 | Schweizerischer Nationalfonds SNF

All articles from Process Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Research finds new molecular structures in boron-based nanoclusters

13.07.2018 | Materials Sciences

Algae Have Land Genes

13.07.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>