Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers create cellular automation model to study complex tumor-host role in cancer

28.03.2012
Cancer remains a medical mystery – despite all of the research efforts devoted to understanding and controlling it. The most sought-after tumor model is one that would be able to formulate theoretical and computational tools to predict cancer progression and propose individual treatment strategies.

To better understand the role complex tumor-host interactions play in tumor growth, Princeton University researchers developed a cellular automation model for tumor growth in heterogeneous microenvironments. They then used this same model to investigate the effects of pressure on the growth of a solid tumor in a confined heterogeneous environment, such as a brain cancer growing in the cranium, and discovered that pressure accumulated during tumor growth can lead to a wide spectrum of growth dynamics and morphologies for both noninvasive and invasive tumors.

Depending on the magnitude of the pressure and the physical properties of the host environment, the types of tumor patterns that emerge range from strongly malignant tumors characterized by finger-like protrusions at the tumor surface to those in which fingering growth is diminished. These results should have important applications for cancer diagnosis, prognosis, and therapy.

Article: "Diversity of dynamics and morphologies of invasive solid tumors" is published in AIP Advances.

Authors: Yang Jiao (1) and Salvatore Torquato (1,2,3,4,5).

(1) Physical Science in Oncology Center, Princeton University, N.J.
(2) Department of Chemistry, Princeton University, N.J.
(3) Department of Physics, Princeton University, N.J.
(4) Princeton Center for Theoretical Science, Princeton University, N.J.
(5) Program in Applied and Computational Mathematics, Princeton University, N.J.

Charles E. Blue | EurekAlert!
Further information:
http://www.aip.org

More articles from Physics and Astronomy:

nachricht Scientists see energy gap modulations in a cuprate superconductor
02.04.2020 | DOE/Brookhaven National Laboratory

nachricht BESSY II: Ultra-fast switching of helicity of circularly polarized light pulses
02.04.2020 | Helmholtz-Zentrum Berlin für Materialien und Energie

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Harnessing the rain for hydrovoltaics

Drops of water falling on or sliding over surfaces may leave behind traces of electrical charge, causing the drops to charge themselves. Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz have now begun a detailed investigation into this phenomenon that accompanies us in every-day life. They developed a method to quantify the charge generation and additionally created a theoretical model to aid understanding. According to the scientists, the observed effect could be a source of generated power and an important building block for understanding frictional electricity.

Water drops sliding over non-conducting surfaces can be found everywhere in our lives: From the dripping of a coffee machine, to a rinse in the shower, to an...

Im Focus: A sensational discovery: Traces of rainforests in West Antarctica

90 million-year-old forest soil provides unexpected evidence for exceptionally warm climate near the South Pole in the Cretaceous

An international team of researchers led by geoscientists from the Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research (AWI) have now...

Im Focus: Blocking the Iron Transport Could Stop Tuberculosis

The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron supply. When the iron transport into the bacteria is inhibited, the pathogen can no longer grow. This opens novel ways to develop targeted tuberculosis drugs.

One of the most devastating pathogens that lives inside human cells is Mycobacterium tuberculosis, the bacillus that causes tuberculosis. According to the...

Im Focus: Physicist from Hannover Develops New Photon Source for Tap-proof Communication

An international team with the participation of Prof. Dr. Michael Kues from the Cluster of Excellence PhoenixD at Leibniz University Hannover has developed a new method for generating quantum-entangled photons in a spectral range of light that was previously inaccessible. The discovery can make the encryption of satellite-based communications much more secure in the future.

A 15-member research team from the UK, Germany and Japan has developed a new method for generating and detecting quantum-entangled photons at a wavelength of...

Im Focus: Junior scientists at the University of Rostock invent a funnel for light

Together with their colleagues from the University of Würzburg, physicists from the group of Professor Alexander Szameit at the University of Rostock have devised a “funnel” for photons. Their discovery was recently published in the renowned journal Science and holds great promise for novel ultra-sensitive detectors as well as innovative applications in telecommunications and information processing.

The quantum-optical properties of light and its interaction with matter has fascinated the Rostock professor Alexander Szameit since College.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

13th AKL – International Laser Technology Congress: May 4–6, 2022 in Aachen – Laser Technology Live already this year!

02.04.2020 | Event News

“4th Hybrid Materials and Structures 2020” takes place over the internet

26.03.2020 | Event News

Most significant international Learning Analytics conference will take place – fully online

23.03.2020 | Event News

 
Latest News

Capturing 3D microstructures in real time

03.04.2020 | Materials Sciences

First SARS-CoV-2 genomes in Austria openly available

03.04.2020 | Life Sciences

Do urban fish exhibit impaired sleep? Light pollution suppresses melatonin production in European perch

03.04.2020 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>