Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


The healing effect of radon


Natural thermal water that contains radon has been used for over 100 years to treat chronic degenerative, inflammatory and musculoskeletal conditions. Most patients experience a significant reduction in pain after treatment with radon, but the molecular mechanisms behind the treatment are largely unexplored. In the placebo-controlled RAD-ON02 study (EudraCT No. 2016-002085-31) in accordance with the German Medicinal Products Act (AMG), the immunological and pain-relieving effects of serial radon baths is now being investigated in patients with musculoskeletal conditions as part of a collaboration between Universitätsklinikum Erlangen and Kurort-Forschungsverein Bad Steben.

Arthritis, osteoarthritis and heel spurs are some of the most common chronic degenerative and musculoskeletal conditions that cause pain and inflammation and thus have an adverse effect on patients’ mobility and quality of life.

Even though a wide range of ‘conventional’ therapies is available, some patients either do not respond well to them or do not respond to them in the long term.

Spa treatment using radon where patients take a series of baths in thermal water that contains radon can offer relief in such cases. Short exposure to the low dose radiation from radon seems to be responsible for the therapeutic effect.

The RAD-ON02 study was initiated in order to gain some scientific evidence for the pain-relieving and immune modulatory effects of radon and its positive effects on bone metabolism.

It is being carried out to the highest quality standards in accordance with the German Medicinal Products Act (AMG). A temporary placebo group will increase the validity of the results of the study.

Any potential side effects of radon baths are being investigated in collaboration with scientists at GSI Helmholtzzentrum für Schwerionenforschung GmbH (GSI Helmholtz Centre for Heavy Ion Research) in Darmstadt, Universitätsklinikum Frankfurt and Technische Universität Darmstadt.

In conjunction with the Bavarian State Spa in Bad Steben, the 100 patients involved in the study will receive a series of radon baths. At first, only half the patients will bathe in water that contains radon, while the other participants will receive a placebo bath without being informed.

All participants will then undergo clinical and immunological testing over a longer period of time. The patient groups will be switched in a second series of baths to enable all patients in the study to take radon baths.

A team led by Dr. Gerhard Klein, who is a specialist in internal medicine and cardiology, will be taking care of the study participants and carrying out the subsequent medical examinations, during which pain perception, effects on the cardiovascular system and the oxidative stress of the patients is measured before and after the baths and evaluated.

Blood taken from the patients is being monitored closely using molecular-biological analysis to track any osteoimmunological changes in detail. Under the leadership of Prof. Dr. Udo Gaipl and PD Dr. Benjamin Frey, the team at the Department of Radiation Oncology in Erlangen is also investigating in particular how the immune status of the patients changes temporarily.

To do so, they will measure the quantity and activation status of 26 different types of immune cells and determine messenger substances in blood serum that are linked to inflammation and bone metabolism.

Wissenschaftliche Ansprechpartner:

Further information:
Prof. Dr. Udo Gaipl
Phone: +49 9131 8532311

Dr. Susanne Langer | idw - Informationsdienst Wissenschaft
Further information:

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Regensburg physicists watch electron transfer in a single molecule

For the first time, an international team of scientists based in Regensburg, Germany, has recorded the orbitals of single molecules in different charge states in a novel type of microscopy. The research findings are published under the title “Mapping orbital changes upon electron transfer with tunneling microscopy on insulators” in the prestigious journal “Nature”.

The building blocks of matter surrounding us are atoms and molecules. The properties of that matter, however, are often not set by these building blocks...

Im Focus: University of Konstanz gains new insights into the recent development of the human immune system

Scientists at the University of Konstanz identify fierce competition between the human immune system and bacterial pathogens

Cell biologists from the University of Konstanz shed light on a recent evolutionary process in the human immune system and publish their findings in the...

Im Focus: Transformation through Light

Laser physicists have taken snapshots of carbon molecules C₆₀ showing how they transform in intense infrared light

When carbon molecules C₆₀ are exposed to an intense infrared light, they change their ball-like structure to a more elongated version. This has now been...

Im Focus: Famous “sandpile model” shown to move like a traveling sand dune

Researchers at IST Austria find new property of important physical model. Results published in PNAS

The so-called Abelian sandpile model has been studied by scientists for more than 30 years to better understand a physical phenomenon called self-organized...

Im Focus: Cryo-force spectroscopy reveals the mechanical properties of DNA components

Physicists from the University of Basel have developed a new method to examine the elasticity and binding properties of DNA molecules on a surface at extremely low temperatures. With a combination of cryo-force spectroscopy and computer simulations, they were able to show that DNA molecules behave like a chain of small coil springs. The researchers reported their findings in Nature Communications.

DNA is not only a popular research topic because it contains the blueprint for life – it can also be used to produce tiny components for technical applications.

All Focus news of the innovation-report >>>



Industry & Economy
Event News

Global Legal Hackathon at HAW Hamburg

11.02.2019 | Event News

The world of quantum chemistry meets in Heidelberg

30.01.2019 | Event News

Our digital society in 2040

16.01.2019 | Event News

Latest News

Gravitational waves will settle cosmic conundrum

15.02.2019 | Physics and Astronomy

Spintronics by 'straintronics'

15.02.2019 | Physics and Astronomy

Platinum nanoparticles for selective treatment of liver cancer cells

15.02.2019 | Life Sciences

Science & Research
Overview of more VideoLinks >>>