Chronic fatigue can negatively affect a person's health-related quality of life and ability to work and carry out normal daily functions. Authors Hanne Hamre, MD and colleagues Oslo University Hospital and University of Oslo Norway used a questionnaire, clinical examination, and blood samples to compare adult survivors of childhood leukemia and lymphoma to a control group from the general population. The prevalence of chronic fatigue was 27% among the cancer survivors compared to 8% among controls.
In the article "High Prevalence of Chronic Fatigue in Adult Long-Term Survivors of Acute Lymphoblastic Leukemia and Lymphoma during Childhood and Adolescence," (http://online.liebertpub.com/doi/full/10.1089/jayao.2012.0015) the authors describe factors predictive of chronic fatigue among the adult cancer survivors and present blood analysis findings suggestive of a persistent low-grade inflammatory response that may contribute to the chronic fatigue.
"Chronic fatigue in cancer survivors is often an under-appreciated complication of treatment," says Editor-in-Chief Leonard S. Sender, MD, of the University of California, Irvine and CHOC Children's Hospital. "There is a general belief that after successful treatment a survivor should be able to bounce back without lasting effects. Hamre and colleagues demonstrate that fatigue is a larger problem than generally appreciated. Their findings put a spotlight on this key aspect of cancer survivorship and serve to encourage the medical community to communicate with cancer survivor patients about possible chronic fatigue."
Vicki Cohn | EurekAlert!
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