Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Soy protein alleviates symptoms of fatty liver disease

23.04.2012
University of Illinois scientists report that soy protein may significantly reduce fat accumulation and triglycerides in the livers of obese persons. And they've discovered why it happens: soy restores partial function of that organ's key signaling pathway.

"Almost a third of American adults have fatty liver disease, many of them without symptoms. Obesity is a key risk factor for this condition, which can lead to liver failure," said Hong Chen, a U of I assistant professor of food science and human nutrition.

Fat is metabolized in the liver, and in obese persons, the transport of fat to adipose tissue can slow down to the point that the liver becomes a dumping ground for excess fat, she said.

"When fat accumulates in an organ that's not supposed to store fat—like the liver, that organ's vital function can be dangerously compromised," she noted.

Adding soy protein, in such sources as tofu and soy yogurt, appears to alleviate some of the stress on fatty livers, she said.

Chen's study compared fat accumulation in the livers of lean and obese rats, which were assigned to either a diet containing casein, a milk-based protein, or a diet containing soy protein isolate, for 17 weeks after weaning. The researchers found that diet had no effect on the liver profiles of lean animals.

But obese rats fed soy showed a 20 percent reduction in triglycerides and overall fat accumulation in the liver, leading Chen to believe that soy protein could be used to alleviate the symptoms of fatty liver disease.

Further, the scientists discovered that soy protein isolate partially restored the Wnt/â-catenin signaling pathway, a crucial player in fat metabolism.

"In many obese persons, there's a sort of traffic problem, and when more fat can make its way out of the liver, there is less pressure on that organ," she said.

The scientists verified the involvement of this pathway by doing in vitro cell culture studies.

Graduate student Dan Zhou found the results especially interesting because of their practical implications. "It's exciting to think that adding soy protein to their diets might help people who have fatty liver disease," she said.

The research will be presented at April's Experimental Biology meeting. Co-authors are Dan Zhou and Huan Wang of the U of I and Jeremy Davis and William Banz of Southern Illinois University. The study was funded by the Illinois Soybean Association and Solae, Inc.

Phyllis Picklesimer | EurekAlert!
Further information:
http://www.illinois.edu

Further reports about: Illinois River Watershed Soy fatty liver liver disease soy protein

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Excitation of robust materials

Kiel physics team observed extremely fast electronic changes in real time in a special material class

In physics, they are currently the subject of intensive research; in electronics, they could enable completely new functions. So-called topological materials...

Im Focus: Electrons in the fast lane

Solar cells based on perovskite compounds could soon make electricity generation from sunlight even more efficient and cheaper. The laboratory efficiency of these perovskite solar cells already exceeds that of the well-known silicon solar cells. An international team led by Stefan Weber from the Max Planck Institute for Polymer Research (MPI-P) in Mainz has found microscopic structures in perovskite crystals that can guide the charge transport in the solar cell. Clever alignment of these "electron highways" could make perovskite solar cells even more powerful.

Solar cells convert sunlight into electricity. During this process, the electrons of the material inside the cell absorb the energy of the light....

Im Focus: The lightest electromagnetic shielding material in the world

Empa researchers have succeeded in applying aerogels to microelectronics: Aerogels based on cellulose nanofibers can effectively shield electromagnetic radiation over a wide frequency range – and they are unrivalled in terms of weight.

Electric motors and electronic devices generate electromagnetic fields that sometimes have to be shielded in order not to affect neighboring electronic...

Im Focus: Gentle wall contact – the right scenario for a fusion power plant

Quasi-continuous power exhaust developed as a wall-friendly method on ASDEX Upgrade

A promising operating mode for the plasma of a future power plant has been developed at the ASDEX Upgrade fusion device at Max Planck Institute for Plasma...

Im Focus: ILA Goes Digital – Automation & Production Technology for Adaptable Aircraft Production

Live event – July 1, 2020 - 11:00 to 11:45 (CET)
"Automation in Aerospace Industry @ Fraunhofer IFAM"

The Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM l Stade is presenting its forward-looking R&D portfolio for the first time at...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Contact Tracing Apps against COVID-19: German National Academy Leopoldina hosts international virtual panel discussion

07.07.2020 | Event News

International conference QuApps shows status quo of quantum technology

02.07.2020 | Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

 
Latest News

On-chip spin-Hall nanograting for simultaneously detecting phase and polarization singularities

08.07.2020 | Physics and Astronomy

Engineers use electricity to clean up toxic water

08.07.2020 | Agricultural and Forestry Science

Atomic 'Swiss army knife' precisely measures materials for quantum computers

08.07.2020 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>