But a review of these guidelines, published in the online open access journal, Arthritis Research & Therapy, found many differences in treatments addressed and a lack of educational information in most of the articles.
An international team of 13 clinical researchers, including rheumatologists, physiotherapists, occupational health experts and general practitioners, scrutinized six sets of knee osteoarthritis treatment guidelines, which were published or updated between 2001 and 2006. Evaluators were trained on how to apply the AGREE criteria to evaluate the guidelines.
Guidelines recommend acetaminophen for initial pain treatment, combined with exercise and education. If acetaminophen fails to control pain, NSAIDs are the next option, but should be used cautiously because of gastro-intestinal (GI) risks. The guidelines indicate surgery for persistent pain and disability. Most guidelines address education and activity management interventions superficially, and the team suggests that these should be detailed in the future.
The guideline effectively addressed only a minority of AGREE domains. “To improve applicability and increase uptake by end users, stakeholder opinions and barriers in use need to be taken into account during guideline development,” the authors say. Guideline development and the spreading of new knowledge are slow processes, and the authors also recommend development of innovative knowledge translation methods to health professionals.
Knee osteoarthritis causes significant costs and disability in the population, and is increasingly prevalent due to higher obesity rates and an aging population.
A review of the quality of knee osteoarthritis guidelines using the AGREE (Appraisal of Guidelines Research and Evaluation) instrument was published in 2002, and concluded that the quality of the guidelines varied and could generally be improved.
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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21.08.2018 | Medical Engineering