But a review of these guidelines, published in the online open access journal, Arthritis Research & Therapy, found many differences in treatments addressed and a lack of educational information in most of the articles.
An international team of 13 clinical researchers, including rheumatologists, physiotherapists, occupational health experts and general practitioners, scrutinized six sets of knee osteoarthritis treatment guidelines, which were published or updated between 2001 and 2006. Evaluators were trained on how to apply the AGREE criteria to evaluate the guidelines.
Guidelines recommend acetaminophen for initial pain treatment, combined with exercise and education. If acetaminophen fails to control pain, NSAIDs are the next option, but should be used cautiously because of gastro-intestinal (GI) risks. The guidelines indicate surgery for persistent pain and disability. Most guidelines address education and activity management interventions superficially, and the team suggests that these should be detailed in the future.
The guideline effectively addressed only a minority of AGREE domains. “To improve applicability and increase uptake by end users, stakeholder opinions and barriers in use need to be taken into account during guideline development,” the authors say. Guideline development and the spreading of new knowledge are slow processes, and the authors also recommend development of innovative knowledge translation methods to health professionals.
Knee osteoarthritis causes significant costs and disability in the population, and is increasingly prevalent due to higher obesity rates and an aging population.
A review of the quality of knee osteoarthritis guidelines using the AGREE (Appraisal of Guidelines Research and Evaluation) instrument was published in 2002, and concluded that the quality of the guidelines varied and could generally be improved.
Potential seen for tailoring treatment for acute myeloid leukemia
10.12.2018 | University of Washington Health Sciences/UW Medicine
UC San Diego researchers develop sensors to detect and measure cancer's ability to spread
06.12.2018 | University of California - San Diego
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.
Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...
New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals
Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.
Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.
Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...
Scientists from the Theory Department of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science (CFEL) in Hamburg have shown through theoretical calculations and computer simulations that the force between electrons and lattice distortions in an atomically thin two-dimensional superconductor can be controlled with virtual photons. This could aid the development of new superconductors for energy-saving devices and many other technical applications.
The vacuum is not empty. It may sound like magic to laypeople but it has occupied physicists since the birth of quantum mechanics.
10.12.2018 | Event News
06.12.2018 | Event News
03.12.2018 | Event News
10.12.2018 | Life Sciences
10.12.2018 | Physics and Astronomy
10.12.2018 | Life Sciences