Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Twice the risk of cervical cancer despite operation

29.10.2007
Women who have had severe cell changes in the cervix and who have been operated on for them run twice the risk of developing cancer later in life, compared with other women. This is shown by research from the Sahlgrenska Academy in Gothenburg Sweeden that is now being published in British Medical Journal.

Swedish women are regularly called in for cell tests. In cases where severe changes in cells are discovered, the outer layer of the portio vaginalis is removed in an operation. Annually some 10,000 women in Sweden undergo this operation for cell changes in the cervix. If the cell changes are left untreated, there is a great risk of developing cervical cancer or vaginal cancer.

But despite this operation and subsequent monitoring, these women still face 2.5 times the risk of developing cervical cancer or vaginal cancer compared with other women. This is shown in a Swedish study now being published in British Medical Journal.

“It is remarkable that the risk of cancer continues to be elevated even though the sections of the tissue where cervical cancer usually starts have been removed,” says the study’s lead author, Björn Strander, a doctoral candidate at the Sahgrenska Academy and chief physician at the Oncology Center for the Western Sweden health-care region.

The researchers have been able to monitor women for more than 25 years after treatment and have found that the risk does not decline substantially after a long period. The elevated risk was greatest among women who were over the age of fifty when they underwent treatment for the cell changes.

¬“The treatments are successful since only about one percent of these women develop cancer, but it appears that women have not been monitored carefully enough with cell samples and not long enough after their treatment,” says Björn Strander.

He therefore feels that it is important to review the special follow-up programs that are offered following treatment for cell changes.

The study was carried out with the aid of the Swedish Cancer Register. This register includes severe cell changes that have not developed into cancer. A total of 132 493 women who have been treated for such cell changes could be followed for an average of 17 years, some of them as long as 40 years.

“Thanks to well-managed and comprehensive registers, we in Sweden can perform epidemiological studies and uncover interesting results that would not be possible in most other countries. They help Sweden maintain its prominent position in medical research,” says Pär Sparén, professor of medical epidemiology at the Karolinska Institute, and co-author of the study.

The study will be included in Björn Strander’s doctoral dissertation, to be submitted in January at the Sahlgrenska Academy. The dissertation is about improving the protection against cervical cancer in Sweden.

Björn Strander | alfa
Further information:
http://www.gu.se

More articles from Health and Medicine:

nachricht Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Foods of the future
15.08.2018 | Georg-August-Universität Göttingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Smallest transistor worldwide switches current with a single atom in solid electrolyte

17.08.2018 | Physics and Astronomy

Robots as Tools and Partners in Rehabilitation

17.08.2018 | Information Technology

Climate Impact Research in Hannover: Small Plants against Large Waves

17.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>