Ana Azevedo and colleagues, from the University of Porto Medical School, Portugal, investigated the possibility of a graded association between the number of features of metabolic syndrome and cardiac structural and functional abnormalities. Their study also investigated whether the associations found were independent of coronary heart disease risk as predicted by the Framingham risk score, a standard tool to predict the probability of having heart disease in the future.
The authors investigated a sample of urban Portuguese adults who were invited to a full screening interview including questionnaires, blood tests for cholesterol and glucose levels, and an ECG measurement. This was followed up with a structured clinical interview including a cardiovascular physical examination, transthoracic echocardiogram and pulsed Doppler evaluation. The results indicated that symptomatic heart failure and severe cardiac structural and functional abnormalities rise progressively with increasing degree of metabolic syndrome, regardless of symptoms. This association was independent of the 10-year predicted risk of coronary heart disease by Framingham risk score for indirect indices of diastolic dysfunction, but not systolic dysfunction.
Unlike in previous studies, the association between metabolic syndrome and heart disease found in this research is not fully explained by blood pressure levels, the authors suggest. “Metabolic syndrome may help predict an increased cardiovascular risk beyond that predicted by the more frequently used Framingham risk score,” Azevedo says.
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Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
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Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur
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Dr. Francisco Garcia-Moreno and his team have designed a turntable that rotates ultra-stably about its axis at a constant rotational speed. This really depends...
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14.08.2018 | Life Sciences