The study investigated male and female twin pairs, aged 7–19 years, to assess the relationship between genetic variations, prenatal substance exposures, and ADHD sub-types. Rosalind Neuman, Ph.D., one of the study’s authors, explains the findings: “When genetic factors are combined with prenatal cigarette smoke exposure, the ADHD risk rises very significantly. When the child has either or both of two specific forms of dopamine pathway genes (DAT and DRD4), and was exposed to cigarette smoking in utero, the risk for having combined type ADHD (many inattention and hyperactive/impulsive symptoms) increased 3 to 9 fold.”
John H. Krystal, M.D., Editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System, adds, “These data highlight a new risk of maternal smoking, increasing the risk for ADHD in their children. ADHD, in turn, increases the risk for substance abuse. Thus, it appears that in utero exposure to nicotine may help to perpetuate a cycle across generations that links addiction and behavioral problems.”
The article is “Prenatal Smoking Exposure and Dopaminergic Genotypes Interact to Cause a Severe Subtype” by Rosalind J. Neuman, Elizabeth Lobos, Wendy Reich, Cynthia A. Henderson, Ling-Wei Sun and Richard D. Todd. All authors are from the Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri. The article appears in Biological Psychiatry, Volume 61, Issue 12 (June 15, 2007), published by Elsevier.
Jayne Dawkins | alfa
The genes are not to blame
20.07.2018 | Technische Universität München
Targeting headaches and tumors with nano-submarines
20.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences