Earlier research had shown that since the introduction of the effective HAART therapy, in 1996, homosexual men have more unsafe sex. Smit established that drug users did not exhibit more risky behaviour once the perspective of HIV-infected drug users improved. Due to improved hygiene drug users acquired less HIV and less hepatitis C.
Smit also examined coinfections. Due to the increased life expectancy relatively more HIV patients have died from other causes in recent years. Infections as a consequence of a reduced immunity (AIDS) remained the number one cause, but the study also revealed an increase in hepatitis and liver-related death. The cause of this was mostly hepatitis C.
Drugs users with both HIV and hepatitis C have a seven times higher chance of dying from liver-related diseases than drug users with just hepatitis C. The side effects of the therapy might also be the cause of the increased chance of liver-related mortality. Patients need to be followed up for longer for definite statements to be made about this.
Smit used data from various studies for her research, some of which were funded by NWO. These studies had mainly been performed in Amsterdam over the past 25 years.
Dr Colette Smit | alfa
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