Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

How is California regulating its $3 billion stem cell research initiative?

08.05.2007
Regulations governing human stem cell research must strive to assure strict oversight while simultaneously fostering scientific innovation through collaboration, says a group of scientists from the California Institute for Regenerative Medicine (CIRM), one of the world's largest supporters of such research.

In November 2004, California voters approved $3 billion over 10 years for public funding of stem cell research through the CIRM. In their policy paper in PLoS Medicine, Geoffrey Lomax, Zach Hall, and Bernard Lo discuss how CIRM came to adopt its legally binding regulations for the stem cell research it funds.

In addition to the goal of "setting high ethical standards," say the authors, there were five other crucial objectives that guided the regulations:

- Encourage research institutions and researchers to develop best practices for ethical conduct of human stem cell research
- Avoid unnecessary regulatory burdens
- Involve the public in developing regulations
- Be consistent with existing laws, regulations, and ethical guidelines
- Facilitate collaboration to accelerate scientific progress.
Dr Lomax and colleagues describe two innovative features of the regulations: the informed consent process and the protection of egg (oocyte) donors.

"Because human embryonic stem cell research is controversial," they say, "prospective donors need complete information about possible research uses of embryos, gametes, and tissue that they might donate. If donors have stated restrictions on the future uses of donated materials, CIRM-funded researchers must respect these."

And for oocyte donors, in addition to obtaining consent, researchers must ascertain that such donors fully comprehend eight essential features of the research. "In other research settings," say Dr Lomax and colleagues, "research participants often fail to understand the information in detailed consent forms." The CIRM regulations require that CIRM researchers evaluate whether women have fully understood the benefits and risks of oocyte donation.

The regulations, they say, were developed with extensive public input and are a “critical first step in increasing public trust and support for human stem cell research.”

Citation: Lomax GP, Hall ZW, Lo B (2007) Responsible oversight of human stem cell research: The California Institute for Regenerative Medicine’s medical and ethical standards. PLoS Med 4(5): e114.

Andrew Hyde | alfa
Further information:
http://www.plosmedicine.org/
http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0040114

More articles from Health and Medicine:

nachricht Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Foods of the future
15.08.2018 | Georg-August-Universität Göttingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Smallest transistor worldwide switches current with a single atom in solid electrolyte

17.08.2018 | Physics and Astronomy

Robots as Tools and Partners in Rehabilitation

17.08.2018 | Information Technology

Climate Impact Research in Hannover: Small Plants against Large Waves

17.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>