Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Early feeding could help reduce liver dysfunction in critically ill patients

26.01.2007
Changing the way that critically ill patients suffering from sepsis or multiple organ failure are fed could reduce liver dysfunction.

A large study published today in the journal Critical Care recommends that clinicians should strictly control calorie intake, start artificial nutrition within 24 hours and regularly monitor liver function in patients at high risk. The researchers find that patients given enteral nutrition were less likely to suffer from liver dysfunction than those fed through a central venous catheter. Liver dysfunction was more frequent in patients who had sepsis on admission or were fed more than 25kcal/kg a day.

The study was conducted by Teodoro Grau, from the Hospital Severo Ochoa in Madrid, Spain, and colleagues from hospitals in Spain and London, UK. The researchers looked at incidence of liver dysfunction associated with artificial nutrition in 40 intensive care units (ICU) in Spain. Patients were followed until hospital discharge or 28 days after ICU admission. Of 3,409 patients in the study, 725 received artificial nutrition. Of these, 303 received total parental nutrition (TPN) via a central venous catheter, while 422 were given enteral nutrition (EN) through a nasogastric or nasojejunal tube, at the doctor’s discretion. 23% (166) of all patients who received artificial nutrition developed liver dysfunction. Rates of liver dysfunction were higher in the TPN group (30%) than in the EN group (18%).

The researchers found that patients who were suffering from sepsis and treated with TPN were at a greater risk of liver dysfunction. Patients receiving TPN were also less nourished.

Liver dysfunction was associated with a longer stay in the ICU and in hospital, but did not increase mortality. Patients who were fed early in their stay had significantly lower incidence of liver dysfunction.

Grace Baynes | alfa
Further information:
http://www.biomedcentral.com

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First diode for magnetic fields

Innsbruck quantum physicists have constructed a diode for magnetic fields and then tested it in the laboratory. The device, developed by the research groups led by the theorist Oriol Romero-Isart and the experimental physicist Gerhard Kirchmair, could open up a number of new applications.

Electric diodes are essential electronic components that conduct electricity in one direction but prevent conduction in the opposite one. They are found at the...

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Helping to Transport Proteins Inside the Cell

21.11.2018 | Life Sciences

Meta-surface corrects for chromatic aberrations across all kinds of lenses

21.11.2018 | Power and Electrical Engineering

Removing toxic mercury from contaminated water

21.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>