Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Glue Ear Could Be Caused By Gastric Juices

08.02.2002


Glue ear — a frequent cause of deafness in children — could be a result of gastric reflux, which results in stomach proteins accumulating in the middle ear via the Eustachian tube, suggest authors of a research letter in this week’s issue of THE LANCET.



Glue ear is common among children after middle-ear infections (otitis media); effusion, produced by mucus cells, occurs in the middle ear and cannot be cleared. It is a particular problem for young children because of the angle and immaturity of the Eustachian tube, and the supine position in which infants are often placed. There are thought to be several causes of glue ear, including bacterial and viral infection, allergy, and the presence of stomach acid (and the enzyme pepsin) as a result of gastric reflux. Andrea Tasker from the University of Newcastle upon Tyne, UK, and colleagues investigated reflux of gastric juice as a potential cause of glue ear.

The investigators measured pepsin concentrations in middle ear effusions from children in Newcastle upon Tyne and Nottingham, UK. 45 (83%) of 54 effusions contained pepsin/pepsinogen at concentrations of up to 1000-fold greater than those in blood (used for comparison).


Andrea Tasker comments: “Gastric juice that refluxes into the middle ear will cause transient damage to the Eustachian tube and the middle-ear mucosa before it can be neutralised, resulting in inflammation. This provides ideal conditions for secondary bacterial colonisation, leading to the symptoms associated with glue ear. We therefore think that anti-reflux treatment could prevent otitis media with effusion.”

Richard Lane | alphagalileo

More articles from Health and Medicine:

nachricht Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University

nachricht Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>