Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sugar not linked with diabetes risk

07.12.2006
It has long been suspected that a high sugar diet over a long term period may lead to an increased risk of developing diabetes. But there has been little or no evidence to support this idea, with studies on the role of any aspect of the diet in the development of diabetes difficult to conduct.

Researchers from the Royal Victoria Hospital and Queen’s University Belfast have just published the results of a clinical trial looking at the effects of high sugar intake on insulin resistance (said to be a precursor of Type 2 diabetes) and vascular health in 13 healthy nondiabetic men.

Sharing their findings in this month’s Diabetes journal, Dr Steven Hunter and his team of researchers report that those who received 25% of their calorie intake from sucrose (sugar) as part of a balanced, weight maintaining diet for 6 weeks showed no difference in their degree of insulin resistance, compared to a eucaloric (calorie matched) diet providing 10% of energy as sucrose (control).

In this study, the 25% treatment diet provided on average 200g sucrose per day compared with 80g sucrose from the control (10%) diet (around the average for a British adult).

Dr Hunter of the Royal Victoria Hospital said: ‘Sugar has traditionally been linked to the development of diabetes. These findings challenge that thinking, and show that intakes of more than double that currently recommended do not appear to have an adverse effect on markers of diabetes risk.”

The study saw 13 healthy men receive either a high-sugar diet (providing 25% of their energy) or a diet providing 10% of their energy as sugar for a period of 6 weeks. After the 6 weeks, subjects ‘crossed over’ to receive the other treatment for a further 6 weeks. Treatments were separated by a four week wash out period, during which the subjects returned to their usual diet.

The diets for each period were closely matched in overall macronutrient (carbohydrate, fat and protein) composition. The only difference was in substituting sucrose (sugar) for starch. Insulin resistance was measured by the research ‘gold standard’; a two-step glucose clamp.

Furthermore, the high sucrose diet showed no significant adverse effects on a number of other metabolic and physiologic parameters, such as elasticity of the arteries (known as vascular compliance) which impacts on risk of heart disease, and glycaemic profiles.

This study showed that an intake of sucrose two and a half times above average consumption levels showed no adverse effects on this important marker of diabetes risk. This study does not therefore support the notion that sugar intake, within a broad range that covers the intake of the majority of British adults has any adverse effect on the risk of diabetes.

Diet can have a large impact on risk of type 2 diabetes; the strongest evidence for a link exists with saturated fat. Dr Hunter advises that the best way of reducing the likelihood of developing diabetes is through lifestyle changes. He adds “It is likely that other dietary factors such as excess calories and lifestyle factors such as physical inactivity and weight gain may be more important than carbohydrate type.”

In people at risk of type 2 diabetes, a diet rich in carbohydrate and low in fat appears to offer protection against insulin resistance. In addition, being of a healthy body weight and maintaining an active lifestyle will help reduce the risk of developing type 2 diabetes.

Richard Cottrell | alfa
Further information:
http://diabetes.diabetesjournals.org/cgi/content/abstract/55/12/3566

More articles from Health and Medicine:

nachricht New antibody analysis accelerates rational vaccine design
09.08.2018 | Scripps Research Institute

nachricht Distrust of power influences choice of medical procedures
01.08.2018 | Johannes Gutenberg-Universität Mainz

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

Im Focus: World record: Fastest 3-D tomographic images at BESSY II

The quality of materials often depends on the manufacturing process. In casting and welding, for example, the rate at which melts solidify and the resulting microstructure of the alloy is important. With metallic foams as well, it depends on exactly how the foaming process takes place. To understand these processes fully requires fast sensing capability. The fastest 3D tomographic images to date have now been achieved at the BESSY II X-ray source operated by the Helmholtz-Zentrum Berlin.

Dr. Francisco Garcia-Moreno and his team have designed a turntable that rotates ultra-stably about its axis at a constant rotational speed. This really depends...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

'Building up' stretchable electronics to be as multipurpose as your smartphone

14.08.2018 | Information Technology

During HIV infection, antibody can block B cells from fighting pathogens

14.08.2018 | Life Sciences

First study on physical properties of giant cancer cells may inform new treatments

14.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>