Clinical and regulatory changes must be made to asthma management to ensure it reflects current scientific understanding of the disease, and the needs of patients, say asthma experts. These conclusions form part of the ‘Brussels Declaration’, defining changes that need to be made in order to improve outcomes for asthma patients, developed by leading asthma experts, together with EU policymakers, regulators and patient groups attending the ‘Summit for Change in Asthma Management’, which took place at the EU Parliament on 18th and 19th October 2006.
Key areas for action identified during the Summit, hosted by Liberal Democrat MEP, Liz Lynne (UK) and co-chaired by leading asthma expert Professor Stephen Holgate of the University of Southampton (UK) include: a rapid need to update national and international clinical guidelines on the treatment of asthma, including the EMEA Guidance Note on Asthma; ensure all patients and professionals fully understand the current thinking behind asthma management; inclusion of wider measures of asthma control in studies and practice, which take into account patient quality of life. In addition, the EU Parliament was encouraged with making asthma, its research and its management a political priority through mechanisms such as the European Parliament Initiative Report.Professor Holgate defines the Summit and the resulting Declaration as a great step forward for asthma management and patients: “This meeting has been extremely valuable as it has allowed health care professionals, scientists and patient groups to work directly with regulators and policymakers to establish where and how improvements need to be made in order for asthma patients to receive optimum treatment. However, our work does not end here; it is vital that all of the actions agreed upon are also acted upon to ensure asthma patients benefit fully.”
During the Summit various clinicians presented information which showed asthma to be a systemic inflammatory disease which affects more than just the lungs and thus the need to control inflammation is essential. However, current guidelines and practice are based on a historical view of diagnosis and treatment of asthma which only measure airflow in the lungs and so may not truly capture whether the inflammation is under control or whether other parts of the body are affected by the same type of inflammation. Furthermore, data also shows that patients respond differently to treatments and one option may not suit all. Therefore treatment should be individualised to meet the needs of the patient. Unfortunately, current methods of assessing therapies that influence the wider aspects of allergic inflammation are not reflected in guidelines which currently are restrictive in their recommendations and limit the choice of treatments available for clinicians to choose from.
The Cost of Asthma
It is estimated that over 30 million people in Europe have asthma and the number is rising.1 In addition, deaths from asthma have reached 180,000 annually 2 and the economic cost of asthma in Europe is thought to be in the region of €17 billion per year with an annual productivity loss estimated at €9.8bn.3 The economic and social costs of asthma are largely due to uncontrolled disease, and are likely to rise as its prevalence, complexity and severity increases4 and therefore improvement in disease control would substantially reduce costs.
Rosie Allan | alfa
The genes are not to blame
20.07.2018 | Technische Universität München
Targeting headaches and tumors with nano-submarines
20.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences