Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Hirsute-s you, Sir! Could super furry animals provide clues for baldness?

29.08.2006
Scientists looking at mice may have discovered why certain people are hairier than others in what could provide clues as to the reason some men go bald prematurely.

The University of Manchester team has laid bare the molecular processes that determine which embryonic skin cells will form into hair follicles and determine the body's hair pattern.

The findings will be of interest to scientists looking at male-pattern baldness but have more direct implications for people who suffer from ectodermal dysplasia - a range of conditions where skin cells fail to develop into other tissue, including hair follicles.

“During human development, skin cells have the ability to turn into other types of cells to form hair follicles, sweat glands, teeth and nails,” said Dr Denis Headon, who led the research. “Which cells are transformed into hair follicles is determined by three proteins that are produced by our genes.

“Our research has identified how one of these proteins working outside of the cell interacts at a molecular level to determine an individual's hair pattern as the embryonic skin spatially organises itself.”

The team found that cells given the genetic command to become hair follicles will send out signals to neighbouring cells to prevent them from doing likewise, so producing a specific hair pattern. They also demonstrated that by hyperactivating the `hair protein' in embryonic mice, young with considerably more fur than normal were produced.

“We were able to change the number of hair follicles in the embryonic mice while they were developing in the womb,” said Dr Headon, who is based in the University's Faculty of Life Sciences.

“The findings could have implications for sufferers of ectodermal dysplasia that are missing this particular protein and who are unable to develop hair follicles during embryonic development.

“The research - while not directly linked to male-pattern baldness - should be of interest to pharmaceutical companies working in this field as understanding the molecular processes at work during follicle development could provide clues as to why follicles shrink and hair growth diminishes in certain men as they get older.”

Aeron Haworth | alfa
Further information:
http://www.manchester.ac.uk

More articles from Health and Medicine:

nachricht New flexible, transparent, wearable biopatch, improves cellular observation, drug delivery
12.11.2018 | Purdue University

nachricht Exosomes 'swarm' to protect against bacteria inhaled through the nose
12.11.2018 | Massachusetts Eye and Ear Infirmary

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

Im Focus: Coping with errors in the quantum age

Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly

The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...

Im Focus: Nanorobots propel through the eye

Scientists developed specially coated nanometer-sized vehicles that can be actively moved through dense tissue like the vitreous of the eye. So far, the transport of nano-vehicles has only been demonstrated in model systems or biological fluids, but not in real tissue. The work was published in the journal Science Advances and constitutes one step further towards nanorobots becoming minimally-invasive tools for precisely delivering medicine to where it is needed.

Researchers of the “Micro, Nano and Molecular Systems” Lab at the Max Planck Institute for Intelligent Systems in Stuttgart, together with an international...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

In focus: Peptides, the “little brothers and sisters” of proteins

12.11.2018 | Life Sciences

Materials scientist creates fabric alternative to batteries for wearable devices

12.11.2018 | Materials Sciences

A two-atom quantum duet

12.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>