Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Combination therapy may improve survival for pancreatic cancer

26.07.2006
Patients with pancreatic cancer, a historically difficult-to-treat cancer with poor survival rates, may benefit from treatments studied in an international, multi-center research trial.

Results of the study, conducted by researchers at the Comprehensive Cancer Center of Wake Forest University Baptist Medical Center and the Centre Hospitalier Lyon Sud in France, have shown that combining chemotherapy with radiation therapy after the surgical removal of cancer in the pancreas may significantly improve survival. The study is published in the August issue of British Journal of Cancer.

"This study built on previous research that showed that the use of a particular chemotherapy agent (gemcitabine) plus radiation therapy might improve survival rates for patients with this devastating cancer," said A. William Blackstock, M.D., associate professor of radiation oncology at Wake Forest Baptist and lead investigator of the study.

The study was initiated to evaluate a course of treatment involving the combination of six weeks of daily radiation therapy to the upper abdomen, concurrent with twice-weekly doses of gemcitabine, followed by two cycles of maintenance doses of gemcitabine alone.

Between June 1999 and October 2003, 46 patients were evaluated in the study. The majority (70 percent) had advanced pancreatic cancer (known as T-3/ T-4) with involvement of the lymph nodes.

The median survival for all the patients in the study was 18.3 months, compared to a national average of 11 months for patients having surgery alone. Sixty-nine percent of the patients were alive at one year and 24 percent were alive at three years.

"The results of our study are promising because they may reflect not only longer survival of these patients, but also an improved local-regional control of the disease. In addition, because lower doses of gemcitabine were used, it proved to be a less toxic approach to treatment," said Blackstock.

Karen Richardson | EurekAlert!
Further information:
http://www.wfubmc.edu

More articles from Health and Medicine:

nachricht Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University

nachricht Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>