Percutaneous image-guided biopsy of renal masses is safe and accurate, and it frequently alters clinical decision making, says a new study from the University of Michigan.
For the study, the researchers reviewed 153 kidney biopsies in 126 patients. The researchers found that more than 60% of patients had a change in their treatment--whether surgery, tumor ablation, chemotherapy or radiation--due to biopsy results, and that as many as 75 unnecessary kidney removals were potentially avoided.
"When a patient has a kidney mass, options include an open surgical procedure or an image-guided percutaneous biopsy. Percutaneous means that the procedure is performed through the skin, through a tiny incision (only 3-4 mm). Imaging guidance (either ultrasound or CT) allows us to watch our needle as it enters the mass, decreasing the risk of damage to adjacent structures and ensuring that we are sampling the correct tissue," said Katherine Maturen, MD, lead author of the study.
Necoya Lightsey | EurekAlert!
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Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
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Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
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