Women pondering hormone-replacement therapy also should consider regular exercise. A new study at the University of Illinois at Urbana-Champaign suggests that being physically fit offsets cognitive declines attributed to long-term therapy.
"This study not only tells us that there is a benefit to being highly fit, it pinpoints where in the brain it matters for postmenopausal women who have been using the two strategies," said lead author Kirk I. Erickson, a postdoctoral researcher at the Beckman Institute for Advanced Science and Technology at Illinois.
The study appeared online this month in advance of regular publication in the journal Neurobiology of Aging. By using magnetic resonance imaging and voxel-based morphometry (VBM), researchers documented the combined effects on specific areas of the brain based on fitness of short- and long-term users of hormone therapy.
Jim Barlow | EurekAlert!
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