The reliability of a prostate cancer-screening test may be compromised by lifestyle and demographic factors, according to a new study. Published in the January 15, 2006 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study reveals the (rate of) change in concentration of prostate specific antigen (PSA) over time--a calculation called PSA velocity--can be significantly affected by age, race, and diet, leading to falsely lower or elevated values and possible misinterpretation by doctors. Single determinations of PSA concentration, the most common use of the PSA screening test, were minimally but significantly affected by age and body mass index (BMI).
Studies have shown a decrease in prostate cancer mortality since 1992 and some researchers attribute a portion of that fall to the widespread adoption of the PSA test. But some experts say that PSA concentration alone causes too many false positives and leads to many unnecessary tests, such as biopsies and transrectal ultrasounds. Investigators continue to refine the test, including developing calculations such as PSA velocity, PSA density, and age-specific PSA, or other tests such as percent free PSA. However, there is poor understanding of the effect of other factors, such as diet, race, and weight on PSA and its related measurements.
Alan R. Kristal, Dr.P.H. of the Fred Hutchinson Cancer Research Center in Seattle and colleagues reviewed PSA and PSA velocity data from 3,341 cancer-free men to determine relationships between PSA tests and demographic and lifestyle factors.
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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