Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sinusitis is common yet often overlooked cause of chronic cough

03.11.2005


New study moves sinusitis into top three reasons for chronic cough



In a new Mayo Clinic study, researchers found that more than one-third of chronic cough patients given a CT scan had sinusitis, inflammation of the sinuses. Findings will be presented at the American College of Chest Physicians CHEST 2005 meeting in Montreal.

"This study suggests that sinusitis is more common than we had previously thought in people with chronic cough," says Kaiser Lim, M.D., lead researcher and Mayo Clinic pulmonologist and allergist. "It also confirms our impression in the chronic cough clinic that many of our patients have underlying sinus inflammation as a cause of their coughs. Our findings in this series of patients place sinusitis among the top three reasons for chronic cough, along with acid reflux and rhinitis, inflammation of the nasal passages."


Chronic cough is defined as a cough lasting over three weeks. According to Dr. Lim, an estimated 23 million Americans see their physicians each year for cough. How many have been coughing for more than 21 days is yet unconfirmed.

Dr. Lim and colleagues conducted this study as a retrospective review of data from 672 chronic cough patients seen at Mayo Clinic over one year. Physicians had obtained CT scans for 132 of these patients suspected of having sinusitis, with significantly abnormal results indicating sinusitis in 49 patients, or 37.1 percent. The more severe the sinus abnormalities found in the CT scans, the more likely the patients were to be ultimately diagnosed with sinusitis as the cause of chronic cough. Physical examination of the nose and mouth did not predict significant sinus abnormalities shown in the CT scans.

The chronic cough patients Dr. Lim studied had been coughing for an average of 52 months. "The diagnosis had not been made for over four years -- and the shame of it is that many of the people had been coughing due to something you could potentially treat," says Dr. Lim.

Dr. Lim explains that sinusitis is often overlooked by physicians as a culprit in chronic cough. In addition, many patients in Dr. Lim’s study had been told by their physicians to learn to live with their coughs.

"It’s also not unusual for chronic coughers to simply give up on getting a diagnosis and treatment for the underlying problem and resign themselves to live with the coughing," says Dr. Lim. "Thus, you find situations like women who have to wear sanitary pads for urinary leakage due to their coughing and men who can’t have hernia surgery because of their constant coughs."

To determine whether sinusitis might be the underlying cause of a patient’s chronic cough, a patient should undergo a complete ear, nose and throat evaluation including rhinoscopy -- a nasal passage exam using a tiny flexible fiberoptic scope -- and/or a CT scan of the sinuses, according to Dr. Lim. "It is hard to make a diagnosis of sinusitis without looking into the nose or with a CT scan of the sinuses," says Dr. Lim. "Symptoms alone do not predict whether you have sinusitis."

Sinusitis can manifest as weeping mucus that drips down the throat, which can cause irritation and prompt coughing. Sinusitis is not only tricky to diagnose but also can be difficult to treat, according to Dr. Lim. Appropriate treatment includes the use of prednisone, antifungal sprays or sinus surgery, depending on the severity of the sinus inflammation. Sinusitis also tends to recur.

Previously, physicians have often lumped sinusitis and its symptoms together with postnasal drip syndrome from rhinitis as a potential cause of chronic cough, says Dr. Lim. "But this is a problem, as the treatment for rhinitis is not the same as for sinusitis," he says. "Medications designed for rhinitis do not penetrate into the sinuses very well."

It’s often difficult to assign a specific cause to chronic cough, according to Dr. Lim. "It’s not uncommon for several illnesses to occur at the same time in the same patient," he says. "That’s why even when an abnormality has been diagnosed, it has to be treated specifically. Only once this abnormality has resolved and in parallel the cough resolves, can you say whether or not the condition diagnosed is causing the cough."

Dr. Lim advocates intensive treatment for sinusitis in chronic coughers. "If the cough doesn’t go away, it’s probably the wrong diagnosis or it has not been treated adequately," he says. "If diagnosed correctly and then treated aggressively, it will go away. You can always repeat the CT scan of the sinuses to document whether or not the treatment is effective in controlling the sinuses."

Researchers do not know why chronic coughers who have sinusitis developed the sinus inflammation.

Lisa Lucier | EurekAlert!
Further information:
http://www.mayoclinic.com

More articles from Health and Medicine:

nachricht Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University

nachricht Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>