Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Neurological disease raises risk of complications from flu

02.11.2005


Study supports annual flu vaccination for children with neurological conditions



As another flu season approaches, patients with neurological and neuromuscular disease are especially vulnerable to respiratory failure caused by influenza. Researchers from The Children’s Hospital of Philadelphia identified this high-risk group of patients, who have recently been added to the list of groups for whom the federal government recommends receiving annual influenza vaccine.

The research is published in the November 2 issue of the Journal of the American Medical Association. The neurological and neuromuscular diseases studied include cerebral palsy, hydrocephalus, muscular dystrophies, spinal muscular atrophy and seizure disorders.


"Our findings support the recent decision of the Advisory Committee on Immunization Practices [ACIP] to add neurological and neuromuscular disease to the list of chronic conditions that warrant annual influenza vaccination," said study leader Ron Keren, M.D., M.P.H., a pediatrician at The Children’s Hospital of Philadelphia. "We hope this news will reach parents of children with these diseases, as well as health care providers."

The ACIP, an expert panel that advises the CDC on national vaccine practice, had previously designated nine groups of chronic medical conditions for which a flu shot is recommended. Among those conditions are asthma, chronic lung disease, heart disease, disorders of hemoglobin such as sickle cell disease, and chronic kidney disease. The Children’s Hospital study considered all those conditions, in addition to neurological and neuromuscular disease, gastroesophageal reflux disease, and history of prematurity.

The researchers studied the hospital records for 745 children hospitalized at Children’s Hospital for influenza during the 2000 to 2004 flu seasons. Of that total, 32 children (4 percent) developed respiratory failure and needed mechanical ventilation. Of all the chronic conditions studied, children with neurological and neuromuscular disease were at the highest risk of respiratory failure, followed by chronic pulmonary disease other than asthma, and cardiac disease.

The link between neurological disease and respiratory failure among children with flu was a new finding, but not surprising, said Dr. Keren. "Children with neurological and neuromuscular disease often have diminished pulmonary function and ability to handle secretions at baseline, and therefore are more vulnerable to respiratory complications of influenza infection."

Rachel Salis-Silverman | EurekAlert!
Further information:
http://www.chop.edu

More articles from Health and Medicine:

nachricht Foods of the future
15.08.2018 | Georg-August-Universität Göttingen

nachricht New antibody analysis accelerates rational vaccine design
09.08.2018 | Scripps Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

Unraveling the nature of 'whistlers' from space in the lab

15.08.2018 | Physics and Astronomy

Diving robots find Antarctic winter seas exhale surprising amounts of carbon dioxide

15.08.2018 | Earth Sciences

Early opaque universe linked to galaxy scarcity

15.08.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>