New scientific evidence that may shed light on why men are more likely than women to develop aggressive forms of skin cancer has been published today in Carcinogenesis. The research carried out by scientists in UCD Conway Institute of Biomolecular & Biomedical Research shows that a gene found only in men is altered by a chemical process, which is in turn linked to aggressive forms of melanoma.
Dr William Gallagher, UCD School of Biomolecular & Biomedical Science and UCD Conway Institute has led the work of a team of researchers who are trying to identify potential biological markers that could flag aggressive forms of melanoma. Using the latest gene chip technology, their work has focused on 66 genes that undergo changes as a melanoma moves from a non-aggressive to an aggressive state. Dr Gallagher and his team have discovered that a common feature among a significant percentage of these genes is that they have been chemically altered by a process called DNA methylation.
One of these genes turned off by this process, TSPY, is located only on the male Y chromosome and, for the first time, may provide a molecular clue to the commonly held belief that men are not only more likely to develop melanoma but that it tends to be more aggressive.
Elaine Quinn | alfa
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences