New research published in the latest issue of the Journal of Applied Toxicology, shows that in experimental mice an estrogen-mimicking chemical, 4-nonylphenol, triggers breast cancer to a greater extent than naturally occurring estrogens based on their relative affinity for the estrogen receptor. 4-Nonylphenol is released into the environment from cleaning materials, textiles, plastics and some paper.
Breast cancer is the most commonly diagnosed cancer in women and environmental factors appear to cause about three-quarters of cases. Many of the environmental factors increase a woman’s levels of the hormone estrogen, which is thought to be a major contributing factor in the disease.
4-Nonylphenol mimics estrogen and is found in the environment, and researchers in the past have found it in drinking water and in some processed foods. In the liver it stimulates an enzyme system that in turn increases the production of estriol, a hormone associated with breast cancer. It also has an affinity for estrogen receptors in breast tissue that trigger growth, and this affinity is 4,000 times less than estrogens.
Polly Young | alfa
New discoveries predict ability to forecast dementia from single molecule
12.12.2018 | UT Southwestern Medical Center
Pain: Perception and motor impulses arise in the brain independently of one another
12.12.2018 | Technische Universität München
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
13.12.2018 | Awards Funding
13.12.2018 | Earth Sciences
13.12.2018 | Materials Sciences