Study finds that poor T cell responsiveness limits current approaches
In recent years, researchers have become increasingly interested in developing therapeutic vaccines. Most Americans are familiar with prophylactic, or preventive vaccines, which protect an individual from infections; examples include the common pediatric vaccines as well as the flu shot. But therapeutic vaccines are designed instead to be administered to patients who have already acquired chronic infections, such as HIV or hepatitis. These therapeutic vaccines aim to enhance the immune systems ability to combat an infectious agent, such as a virus. Researchers are also developing therapeutic vaccines to treat a variety of cancers.
But many experimental therapeutic vaccines have thus far fallen short of expectations. Now, scientists at The Wistar Institute and Emory University offer details about what may prevent the immune system from responding effectively to a therapeutic vaccine during a state of chronic infection. Their findings suggest how scientists might alter therapeutic vaccination approaches to make the immune system respond better. Their work is published today in the Journal of Virology.
Franklin Hoke | EurekAlert!
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Researchers from the University of Basel have reported a new method that allows the physical state of just a few atoms or molecules within a network to be controlled. It is based on the spontaneous self-organization of molecules into extensive networks with pores about one nanometer in size. In the journal ‘small’, the physicists reported on their investigations, which could be of particular importance for the development of new storage devices.
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A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
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A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
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