“Positron Emission Topography with choline demonstrates greater efficiency in the early diagnosis of relapsed prostate cancer with respect to other imaging techniques”, stated Dr. Macarena Rodríguez, of the Nuclear Medicine Service at the University Hospital of the University of Navarra. She was speaking on receiving the award for the best scientific work at the XXVI National Congress of the Spanish Society for Nuclear Medicine (SEMN), held recently in Maspalomas (the Canary Islands).
The study, entitled, “Value of PET with FDG and 11C-Choline in early diagnosis of relapsed treated prostate carcinoma”, has analysed for the first time in Spain the utility of 11C-Choline for the detection of relapses in these tumours. To date, conventional FDG (F18-fluorodeoxyglucose) has been used as a radiopharmaceutical, offering good specificity but poor sensitivity in the diagnosis of relapsed prostate carcinoma. The research centred on the analysis of the role of the choline and compared it with the results using FDG.
The research, carried out with 38 patients at the Navarre University Hospital, found that 11C-Choline gives better results in diagnosing relapsed prostate cancer. Although both radiopharmaceuticals have a specificity and a predictive negative value of 100%, 11C-Choline shows a sensitivity of 65% in the detection of relapses with low PSA (prostate-specific antigen) level, compared to 28% of FDG. Thus, it is shown to be a radiopharmaceutical especially useful for the early detection of relapsed prostate carcinoma. What is needed now are more studies to enable comparison of its results in function of the treatment that primary tumours require - radiotherapy, surgery, etc.
Garazi Andonegi | alfa
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For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
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Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
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Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
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Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
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