Two University of Kentucky researchers continue their work with a vaccine to prevent lung cancer recurrences in patients following primary treatment of the disease.
Vaccines are being developed with the hope of reducing the unacceptably high rates of recurrence and disease progression seen in the treated lung cancer population. The cancer vaccine program is now enrolling a second cohort of subjects to study the effects of the vaccine in lung cancer patients. The vaccine is delivered following conventional treatment with surgery, radiation therapy or chemotherapy and the patients evaluated for immune responses that could indicate clinical benefit.
Edward A. Hirschowitz, M.D., Associate professor of medicine, and John Yannelli, Ph.D., Associate professor of Microbiology and Immunology, both in the UK College of Medicine, are using white blood cells from the patients blood to make the vaccine. They then administer the vaccine to the patient which allows the patients immune system to recognize and destroy tumor cells that can lead to recurrences after cancer treatment.
Louise DuPont | EurekAlert!
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