The Moscow scientists have conducted clinical trials of a new method for treatment of deep burns of cornea. Their effort has been supported by the Russian Foundation for Basic Research.
Specialists of the Koltsov Institute of Developmental Biology, Russian Academy of Sciences, and the Gelmgolts Scientific Research Institute of Eye Diseases suggest that deep burns of cornea should be treated by transplanting artificial equivalent of stroma (the tissue directly underlying the cornea) on the affected area. The researchers have developed technique for preparation and transplantation of live equivalent of stroma (LES) and tested it in the clinic on patients with heavy burns of eyes. They managed to help the overwhelming majority of patients.
The share of burns among all eye traumas makes about 38 percent, with considerable proportion of cases involving cornea damage. The cornea is supported by the stroma connective tissue, which also gets damaged in case of deep burns. If the stroma is missing or significantly destroyed, the remaining cornea cells are unable to recover injuries as they have no support. Therefore, the major task in treating cornea defects is stroma recovery. This task is convenient to solve via tissue transfer. Foreign researchers suggest that cell culture taken from a healthy eye should be transplanted on the burnt area. However, such operation poses a serious trauma by itself, which is not always justified.
Sergey Komarov | alfa
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