Duke University Medical Center researchers have found that joints whose cartilage lacks a specific type of collagen will develop osteoarthritis – the so-called "wear-and-tear" form of the disease – at a greatly accelerated rate.
The results of their experiments with mice provide new insights that could lead to potential treatments for a disease that afflicts more than 40 million Americans, said the researchers.
The researchers found that mice lacking the gene that controls the production of type VI collagen developed osteoarthritis at a rate more than five times greater than mice with a functioning gene. Collagen is a ubiquitous protein found throughout the body in connective tissue, muscle, cartilage and bone. To date, 27 different types have been identified.
Richard Merritt | EurekAlert!
Researchers image atomic structure of important immune regulator
11.12.2018 | Brigham and Women's Hospital
Potential seen for tailoring treatment for acute myeloid leukemia
10.12.2018 | University of Washington Health Sciences/UW Medicine
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.
Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...
New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals
Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.
Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.
Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...
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