A novel technology that can test cells in minutes for responses to any stimulus, including antibiotics, pathogens, toxins, radiation or chemotherapy, has been developed by scientists at the University at Buffalo.
The paper describing the sensor will appear in the Feb. 15 issue of Analytical Chemistry, and currently is available as an "ASAP" article on the American Chemical Society Web site http://www.chemistry.org.
Susan Z. Hua, Ph.D., UB assistant professor of mechanical and aerospace engineering and physiology and biophysics, is the lead researcher. The technology is based on the universal connection between cell volume and the cell environment, or cell volume cytometry. It is particularly useful because it eliminates the need to culture bacteria to assess their sensitivity to antibiotics. "Now, in a matter of minutes, we can tell if particular antibiotics are active against specific bacteria," said Frederick Sachs, Ph.D., professor of physiology and biophysics at UB, co-director of UB’s Center for Single Molecule Biophysics and a coauthor on the paper. "We have measured the sensitivity to antibiotics of different strains of E. Coli in less than 10 minutes at room temperature. We will get results even faster at higher temperatures."
Using fragment-based approaches to discover new antibiotics
21.06.2018 | SLAS (Society for Laboratory Automation and Screening)
Scientists learn more about how gene linked to autism affects brain
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In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...
Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
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