Statistical physics approach to analysis of heartbeat pattern uncovers link to circadian cycle
In a newly reported, first-ever finding, physicists from Boston University and physiologists from Boston’s Brigham and Women’s Hospital (BWH) have found that the body’s biological clock affects the patterns of heart-rate control in healthy individuals independent of sleep/wake cycle or other behavior influences. Their analysis of the heartbeat dynamics of the healthy individuals in the study showed significant circadian rhythm, including a notable response at the internal circadian phase corresponding to 10 a.m., the time of day most often linked to adverse cardiac events in individuals with heart disease.
The BU/BWH team reports its findings in the Dec. 28 issue of the Proceedings of the National Academy of Sciences. Sponsored by grants from the National Institutes of Health, the institutional teams were led by Plamen Ivanov, a research associate in BU’s Center for Polymer Studies, who undertook the analysis of the data, and Steven Shea, director of BWH’s medical chronobiology program and associate professor of medicine at Harvard Medical School, who conducted the experimental part of the research.
Ann Marie Menting | EurekAlert!
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