Transplant recipients have 96 percent survival rate after first year
Transplant researchers at the University of Pittsburghs Thomas E. Starzl Transplantation Institute have dramatically improved intestinal transplant graft survival, and reduced rejection and infection rates by successfully using a novel immunosuppression minimization protocol, thus improving patients overall quality of life and avoiding the use of several anti-rejection drugs, which can cause serious infections and major complications. Because the intestine is especially prone to rejection and infection, results of this innovative clinical protocol presented today at the 3rd International Conference on Immunosuppression at the Manchester Grand Hyatt, San Diego, are significant and have the potential to advance the field of organ transplantation.
"Transplant recipients do not want to be overwhelmed with a lot of anti-rejection medications, which can often lead to more complications. The fact that we have been able to significantly reduce the amount of anti-rejection drugs in this group of patients has enabled many of them to live full and productive lives," said Kareem Abu-Elmagd, M.D., Ph.D., F.A.C.S., professor of surgery at the University of Pittsburgh School of Medicine and director of the Intestinal Rehabilitation and Transplant Center at the University of Pittsburgh Medical Centers (UPMC) Thomas E. Starzl Transplantation Institute and lead author of the study.
Maureen McGaffin | EurekAlert!
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