Lower sensitivity of mammography in women aged 40 to 49 years compared with older women can be largely explained by greater breast density and rapid tumor growth in the younger women, according to a new study in the October 6 issue of the Journal of the National Cancer Institute.
Because mammography is imperfect for women in their 40s, there has been controversy over whether and how often these women should be screened. Mammographic sensitivity--that is, the percentage of cancers detected by a mammogram--is lower in this group of women than in older women. Several factors have been suggested as contributing to the lower mammographic sensitivity, including higher breast density, faster tumor growth rate, and differences in the distribution of breast cancer risk factors.
To analyze the relative contributions of these factors to differences in mammographic sensitivity between younger and older women, Diana S. M. Buist, Ph.D., of Group Health Cooperative in Seattle, and colleagues studied 576 women (73 aged 40 to 49 years and 503 aged 50 years and older) who were diagnosed with invasive breast cancer between 1988 and 1993. They looked at associations between potential explanatory factors and the odds of having an interval cancer (cancer diagnosed within 12 or 24 months after a negative screening mammogram and before a subsequent mammogram).
Sarah L. Zielinski | EurekAlert!
Study tracks inner workings of the brain with new biosensor
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There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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20.08.2018 | Information Technology